Curated scientific studies with plain-English summaries and multi-paradigm interpretation
Showing 8 studies
DiNicolantonio et al. • Open Heart • 2018
10-30% of populations have subclinical deficiency (<0.80 mmol/L); 48-50% US consumes below RDA; serum reflects <1% of body stores; linked to hypertension, arrhythmias, atherosclerosis, heart failure
Workinger et al. • Nutrients • 2018
Blood magnesium represents only 0.8% of total body stores; 45% of Americans are magnesium deficient; 60% of adults do not reach recommended intake levels
Costello et al. • Advances in Nutrition • 2016
Proposed optimal threshold: ≥0.85 mmol/L (vs current 0.75 mmol/L); CVD risk increases at <0.75-0.85 mmol/L; T2D risk elevated at <0.74 mmol/L
Fang et al. • Nutrients • 2016
Per 100 mg/day increment in magnesium intake: 8-13% reduction in T2D incidence (RR = 0.88-0.92, 95% CI)
Gröber et al. • Nutrients • 2015
Nearly 50% US adults have inadequate Mg intake; hypomagnesemia <0.75 mmol/L; diabetes meta-analysis: RR 0.85 per 100 mg/day increase; 13.5-47.7% of diabetics have hypomagnesemia
Barbagallo & Dominguez • World Journal of Diabetes • 2015
Type 2 diabetes frequently associated with extracellular and intracellular magnesium deficits; intracellular Mg critical for insulin action and glucose uptake; benefits of supplementation found in most studies
Rosanoff A et al. • Nutr Rev • 2012
Up to 50% of Americans don't meet magnesium RDA
Guerrero-Romero F, Rodríguez-Morán M • Acta Diabetol • 2002
Low magnesium strongly associated with metabolic syndrome