B
Good ConfidenceExtreme High HDL Paradoxically Associated with High Mortality
Madsen CM, et al • Eur Heart J
Key Finding
Very high HDL cholesterol is paradoxically associated with increased mortality.
Original title: “Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies”
Plain English Summary
Danish study showing U-shaped relationship between HDL and mortality.
Paradigm Relevance
How this study applies to different clinical perspectives:
Standard Medical
Conventional clinical guidelines used by most doctors
Not directly relevant to this paradigm
Research Consensus
RelevantCurrent scientific understanding, often ahead of guidelines
Metabolic Optimization
RelevantProactive targets for optimal health, not just disease absence
Study Details
- Type
- Cohort Study
Related Biomarkers
HDL CHOLESTEROL