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B
Good Confidence
Cohort Study2012

HDL and MI Risk: A Mendelian Randomisation Study

Voight BF, et alLancet

Key Finding

Genetically raised HDL does not protect against myocardial infarction.

Original title: Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Plain English Summary

Genetic study showing raising HDL does not reduce heart attack risk, challenging the HDL hypothesis.

Paradigm Relevance

How this study applies to different clinical perspectives:

Standard Medical

Conventional clinical guidelines used by most doctors

Not directly relevant to this paradigm

Research Consensus

Relevant

Current scientific understanding, often ahead of guidelines

Metabolic Optimization

Proactive targets for optimal health, not just disease absence

Not directly relevant to this paradigm

Study Details

Type
Cohort Study

Related Biomarkers

HDL CHOLESTEROL

Original Source