Atherogenic Index of Plasma (AIP) Calculator
Metabolic Relevance
AIP = log₁₀(Triglycerides/HDL-C) correlates strongly with LDL particle size (r = 0.803). A negative AIP indicates HDL exceeds triglycerides — representing excellent cardiovascular protection. Dobiásová validation studies established AIP as a powerful predictor of atherosclerosis risk.
Recommended testing frequency:
Every 3-6 months with lipid panels, especially when monitoring metabolic interventions
Did you know?
AIP can be negative! When HDL exceeds triglycerides, the logarithm becomes negative — indicating large buoyant LDL particles and excellent cardiovascular protection. Athletes and low-carb dieters often achieve negative AIP values.
AIP responds faster to dietary changes than LDL-C. Carbohydrate reduction can dramatically lower triglycerides within 2-4 weeks, rapidly improving your AIP score.
Want to understand your result better?
Learn about interpretation, what affects your score, and evidence-based strategies to improve it.
Read the full guideEvidence-Based
This calculator is based on peer-reviewed research validated across thousands of clinical studies.
View scientific references(4)Medical Disclaimer
Why Optimal Thresholds Differ?
Standard Medical
⚠️ Population-level cardiovascular risk stratification
Research Consensus
✓ Negative AIP = HDL exceeds TG, optimal protection
Metabolic Optimization
🔬 Excellent TG reduction with carbohydrate restriction
