Chronic Coronary Syndrome in Mexico: Insights and Implications

Chronic coronary syndromes (CCS) are a significant health concern, particularly in Latin America, where their clinical profiles may differ from those observed in high-income countries. Understanding the unique characteristics of CCS in this region is crucial for tailoring effective treatment and prevention strategies. A recent study involving the Mexican Chronic Coronary Syndrome Registry (RESINCCRO) sheds light on the clinical presentation, coronary anatomy, and treatment patterns of adults living with CCS in Mexico. The RESINCCRO registry included 3,029 adults, predominantly male (72.5%), with a mean age of 67.2 years. The study revealed a high prevalence of cardiometabolic comorbidities among participants, including overweight/obesity (76%), arterial hypertension (69%), type 2 diabetes (44%), and chronic kidney disease (24.2%). Notably, 23.9% of participants experienced persistent angina, with the majority classified as Canadian Cardiovascular Society class I-II (91.2%). The mean left ventricular ejection fraction (LVEF) was recorded at 53.7%, indicating potential heart function impairment. Alarmingly, only 6.2% of participants engaged in cardiac rehabilitation, highlighting a significant gap in post-diagnosis care. Despite a high prescription rate of lipid-lowering therapies, including statins (93.2%), the median LDL-C level was 70 mg/dL, with only 26.1% achieving an LDL-C target of <55 mg/dL. Furthermore, 60.3% of participants had obstructive epicardial disease, underscoring the severity of coronary artery involvement. These findings underscore the urgent need for intensified secondary prevention strategies in Mexico. Healthcare providers should focus on improving the management of cardiometabolic comorbidities and enhancing patient engagement in cardiac rehabilitation programs. This can lead to better health outcomes for individuals living with CCS. Patients are encouraged to discuss their treatment options with healthcare professionals and consider lifestyle modifications, such as dietary changes and increased physical activity, to manage their cardiovascular health effectively. The research highlights several biomarkers relevant to metabolic health, including LDL cholesterol (LDL-C), which is crucial for assessing cardiovascular risk. The high prevalence of obesity and diabetes among participants indicates a need for regular monitoring of fasting glucose and insulin levels, as well as other markers like hsCRP for inflammation. These biomarkers can be evaluated using Metabolicum's calculators, providing users with insights into their metabolic health and guiding necessary interventions. In conclusion, the study on chronic coronary syndrome in Mexico reveals a concerning cardiometabolic burden among adults. The findings emphasize the importance of tailored treatment approaches and the need for increased awareness and participation in cardiac rehabilitation. By addressing these issues, we can improve care for individuals with CCS and promote better metabolic health outcomes in the population.