PubMedJuly 17, 2026
The Alarming Rise of Metabolic Diseases: A Call for Prevention
by Tim Noakes, MD
Metabolic diseases have surged since 1975, with only 6.8% of Americans metabolically healthy. Fasting insulin testing could be key to prevention.
Key Findings
- 1Alzheimer's cases increased from 1 million to 7.1 million since 1975, a 7-fold rise.
- 2Diabetes prevalence has nearly quadrupled from 3.2% to 12% in the same period.
- 3Heart disease cases rose from 25 million to 86 million, reflecting a 3.4-fold increase.
- 4Obesity rates have tripled from 15% to 40%, indicating a significant public health issue.
- 5Prescription drug spending has surged from $10 billion in 1975 to $487 billion in 2025, highlighting a focus on treatment over prevention.
- 6Only 6.8% of American adults are metabolically healthy, with 93% having at least one broken metabolic marker.
The statistics presented by Prof. Tim Noakes highlight a troubling trend in metabolic health over the past 50 years. Diseases such as Alzheimer’s, diabetes, heart disease, obesity, and cancer have all seen significant increases in prevalence. For instance, the number of people living with Alzheimer’s has skyrocketed from 1 million to 7.1 million, a staggering 7-fold increase. Diabetes rates have nearly quadrupled from 3.2% to 12%, and heart disease cases have risen from 25 million to 86 million, reflecting a 3.4-fold increase. Meanwhile, obesity rates have tripled from 15% to 40%, and new cancer cases have doubled from 1 million to 2 million annually. This data paints a stark picture of declining metabolic health, with only 6.8% of American adults considered metabolically healthy, according to research from UNC Chapel Hill.
The increase in prescription drug spending, from $10 billion in 1975 to an estimated $487 billion in 2025, further underscores the failure of our current medical system to prevent these diseases. Instead of focusing on prevention, the healthcare system has become a revenue-generating machine, treating diseases rather than addressing their root causes. This is not merely a failure of medicine; it is medicine functioning as designed, where every diagnosis becomes a revenue stream and every drug a subscription service.
For individuals seeking to improve their metabolic health, understanding the importance of fasting insulin levels is crucial. This simple test, which costs less than $20, can reveal underlying insulin resistance, a common precursor to many of the diseases mentioned. By prioritizing metabolic health through lifestyle changes such as adopting a low-carb or ketogenic diet, engaging in regular physical activity, and managing stress, individuals can take proactive steps towards prevention.
The connection to biomarkers is significant. Key indicators such as fasting insulin, HOMA-IR, fasting glucose, and triglycerides can provide insights into one’s metabolic health status. Utilizing tools like Metabolicum's calculators can help individuals track these biomarkers and make informed decisions about their health.
In conclusion, the alarming rise in metabolic diseases calls for a shift in focus from treatment to prevention. By understanding and monitoring key biomarkers, individuals can take charge of their health and work towards a healthier future. The time for action is now, and it starts with awareness and proactive measures to improve metabolic health.
Related Biomarkers
FASTING INSULINHOMA IRFASTING GLUCOSETRIGLYCERIDES
Calculate & Evaluate on Metabolicum
Original Source
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